Abstract

Objective: to study about the prevalence of strabismus and its types in patients with parental consanguinity

Materials and methods: A search of the literature on strabismus and its correlation to parental consanguinity using PubMed database. Articles obtained regarding strabismus, its types, the rate of strabismus and the presence of consanguinity were critically reviewed. The data of patients were collected with a positive parental consanguinity and diagnosed with strabismus. A pedigree charting was done for all the patients where the degree of relation was assessed, along with the categorization of the type of strabismus along with the degree of refractive error associated with each patient. The categorization of strabismus into infantile esotropia, accommodative esotropia, intermittent or constant exotropia, non – accommodative esotropia, accommodative esotropia. The coefficient of inbreeding was also assessed.

Results: It was seen that parental consanguinity is related with horizontal deviation along with refractive errors. In these patients, the presence of strabismus appears to be mostly in hypermetropic accommodative esotropia. A study stating that the prevalence of strabismus in the first – degree relatives is the highest in accommodative esotropia followed by partial accommodative and lastly with infantile esotropia. The coefficient of inbreeding was significantly higher in the group with strabismus than the control group. The non-accommodative acquired esotropia had the highest mean of inbreeding coefficient.

Conclusion: consanguinity is originated based on the community. Counseling in such communities is key to decrease the associated risk factors in offspring in such communities. The presence of parental consanguinity was higher in the strabismus group with the variations of degree based on the type of strabismus. this correlation needs to be assessed further with increased accuracy and precision with more detailed categorization.

Keywords: strabismus, parental consanguinity, correlation, consanguinity, hereditary, risk factor

Download the full research study here: Jayaraj, J. (2022). Correlation of Parental Consanguinity and Strabismus. SAERA School of Advanced Education, Research and Accreditation